Rabbit Secondary Antibodies
ABclonal Technology 594 Rabbit anti-Human IL23R
The protein encoded by this gene is a subunit of the receptor for IL23A IL23 This protein pairs with the receptor molecule IL12RB1 IL12Rbeta1 and both are required for IL23A signaling This protein associates constitutively with Janus kinase 2 (JAK2) and also binds to transcription activator STAT3 in a ligand-dependent manner
ABclonal Technology 594 Rabbit anti-Human CD2
The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition A locus control region (LCR) has been found in the 3 -apos flanking sequence of this gene [provided by RefSeq Jun 2016]
Jackson Immuno Research Labs Alexa Fluor 488-AffiniPure Rabbit Anti-Human IgM Fc5µ Fragment Specific (min X Ms Sr Prot)
Alexa Fluor 488-AffiniPure Rabbit Anti-Human IgM Fc5µ Fragment Specific (min X Ms Sr Prot)
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure Rabbit Anti-Human IgG Fcγ Fragment Specific
Fluorescein (FITC)-AffiniPure Rabbit Anti-Human IgG Fcγ Fragment Specific
ABclonal Technology 647 Rabbit anti-Human TREM1
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines as well as increased surface expression of cell activation markers Alternatively spliced transcript variants encoding different isoforms have been noted for this gene
ABclonal Technology 594 Rabbit anti-Human CD47
This gene encodes a membrane protein which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin and it may play a role in membrane transport and signal transduction This gene has broad tissue distribution and is reduced in expression on Rh erythrocytes Alternatively spliced transcript variants have been found for this gene
ABclonal Technology 488 Rabbit anti-Human TROP-2
This intronless gene encodes a carcinoma-associated antigen This antigen is a cell surface receptor that transduces calcium signals Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy
ABclonal Technology 594 Rabbit anti-Human SIGLEC9
Predicted to enable monosaccharide binding activity and sialic acid binding activity Predicted to be involved in cell adhesion Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis engulfment Predicted to be located in external side of plasma membrane Predicted to be active in plasma membrane
ABclonal Technology 450 Rabbit anti-Human CD9
This gene encodes a member of the transmembrane 4 superfamily also known as the tetraspanin family Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins The encoded protein functions in many cellular processes including differentiation adhesion and signal transduction and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis
Jackson Immuno Research Labs Alexa Fluor 647-AffiniPure F(ab')2 Fragment Rabbit Anti-Human IgG Fcγ Fragment Specific
Alexa Fluor 647-AffiniPure F(ab')2 Fragment Rabbit Anti-Human IgG Fcγ Fragment Specific
ABclonal Technology PE Rabbit anti-Human TMPRSS2
This gene encodes a protein that belongs to the serine protease family The encoded protein contains a type II transmembrane domain a receptor class A domain a scavenger receptor cysteine-rich domain and a protease domain Serine proteases are known to be involved in many physiological and pathological processes This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E MERS-CoV SARS-CoV and SARS-CoV-2 (COVID-19 virus) Alternatively spliced transcript variants encoding different isoforms have been found for this gene
ABclonal Technology APC Rabbit anti-Human CD177
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration Mutations in this gene are associated with myeloproliferative diseases Over-expression of this gene has been found in patients with polycythemia rubra vera Autoantibodies against the protein may result in pulmonary transfusion reactions and it may be involved in Wegener s granulomatosis A related pseudogene which is adjacent to this gene on chromosome 19 has been identified
ABclonal Technology 488 Rabbit anti-Human TROP-2
This intronless gene encodes a carcinoma-associated antigen This antigen is a cell surface receptor that transduces calcium signals Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy